• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MMP-19 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HUVEC cells, using MMP-19 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using MMP-19 Polyclonal Antibody diluted at 1：500

Anti-MMP19 antibody (11-60) (STJ94162)

SKU:
STJ94162

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Matrix metalloproteinase-19 (11-60) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MMP19
Gene ID: 4327
Uniprot ID: MMP19_HUMAN
Immunogen Region: 11-60
Specificity: MMP-19 Polyclonal Antibody detects endogenous levels of MMP-19 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human MMP-19. AA range:11-60
Tissue Specificity Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and rheumatoid patients.
Post Translational Modifications Activated by autolytic cleavage after Lys-97. Tyrosine phosphorylated by PKDCC/VLK.
Function Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
Protein Name Matrix Metalloproteinase-19
Mmp-19
Matrix Metalloproteinase Rasi
Matrix Metalloproteinase-18
Mmp-18
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1474228
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Matrix Metalloproteinase-19 antibody
Anti-Mmp-19 antibody
Anti-Matrix Metalloproteinase Rasi antibody
Anti-Matrix Metalloproteinase-18 antibody
Anti-Mmp-18 antibody
Anti-MMP19 antibody
Anti-MMP18 antibody
Anti-RASI antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance