| Host: |
Rabbit |
| Applications: |
IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-METTL2A (139-378) is suitable for use in Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
METTL2A |
| Gene ID: |
339175 |
| Uniprot ID: |
MET2A_HUMAN |
| Immunogen Region: |
139-378 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 139-378 of human METTL2A (NP_859076.3). |
| Immunogen Sequence: |
EQHKCSSKSLEHKTQTLPVE ENVTQKISDLEICADEFPGS SATYRILEVGCGVGNTVFPI LQTNNDPGLFVYCCDFSSTA IELVQTNSEYDPSRCFAFVH DLCDEEKSYPVPKGSLDIII LIFVLSAIVPDKMQKAINRL SRLLKPGGMMLLRDYGRYDM AQLRFKKGQCLSGNFYVRGD GTRVYFFTQEELDTLFTTAG LEKVQNLVDRRLQVNRGKQL TMYRVWIQCKYCKPLLSST |
| Function | S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). N(3)-methylcytidine methylation by METTL2A requires the N6-threonylcarbamoylation of tRNA (t6A37) by the EKC/KEOPS complex as prerequisite. |
| Protein Name | Trna N(3-Methylcytidine Methyltransferase Mettl2aMethyltransferase-Like Protein 2a |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Trna N(3-Methylcytidine Methyltransferase Mettl2a antibodyAnti-Methyltransferase-Like Protein 2a antibodyAnti-METTL2A antibodyAnti-METTL2 antibodyAnti-HSPC266 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
