Anti-MARS antibody (1-270) (STJ111979)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MARS (1-270) antibody for use in WB, IHC-P and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MARS1 |
| Gene ID | 4141 |
| Uniprot ID | SYMC_HUMAN |
| Immunogen Region | 1-270 |
| Immunogen Sequence | MRLFVSDGVPGCLPVLAAAG RARGRAEVLISTVGPEDCVV PFLTRPKVPVLQLDSGNYLF STSAICRYFFLLSGWEQDDL TNQWLEWEATELQPALSAAL YYLVVQGKKGEDVLGSVRRA LTHIDHSLSRQNCPFLAGET ESLADIVLWGALYPLLQDPA YLPEELSALHSWFQTLSTQE PCQRAAETVLKQQGVLALRP YLQKQPQPSPAEGRAVTNEP EEEELATLSEEEIAMAVTA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MARS (NP_004981.2). |
Additional Info
| Function | Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Plays a role in the synthesis of ribosomal RNA in the nucleolus. |
| Protein Name | Methionine--Trna Ligase - CytoplasmicMethionyl-Trna SynthetaseMetrs |
| Database Links | Reactome: R-HSA-2408522Reactome: R-HSA-379716Reactome: R-HSA-9856649 |
| Cellular Localisation | CytoplasmCytosolNucleusNucleolusLocalizes To The Nucleolus In Proliferative Cells But Disappears In Quiescent Cells |
| Alternative Antibody Names | Anti-Methionine--Trna Ligase - Cytoplasmic antibodyAnti-Methionyl-Trna Synthetase antibodyAnti-Metrs antibodyAnti-MARS1 antibodyAnti-MARS antibody |
Information sourced from Uniprot.org