Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-MARCH9 (277-346) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MARCHF9 |
Gene ID: |
92979 |
Uniprot ID: |
MARH9_HUMAN |
Immunogen Region: |
277-346 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 277-346 of human MARCH9 (NP_612405.2). |
Immunogen Sequence: |
GTAGKSGPRNSRTGPTSGAT SRPPAAQRMRTLLPQRCGYT ILHLLGQLRPPDARSSSHSG REVVMRVTTV |
Tissue Specificity | Ubiquitously expressed. |
Function | E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I, CD4 and ICAM1, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
Protein Name | E3 Ubiquitin-Protein Ligase Marchf9Membrane-Associated Ring Finger Protein 9Membrane-Associated Ring-Ch Protein IxMarch-IxRing Finger Protein 179Ring-Type E3 Ubiquitin Transferase Marchf9 |
Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinLysosome Membrane |
Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Marchf9 antibodyAnti-Membrane-Associated Ring Finger Protein 9 antibodyAnti-Membrane-Associated Ring-Ch Protein Ix antibodyAnti-March-Ix antibodyAnti-Ring Finger Protein 179 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Marchf9 antibodyAnti-MARCHF9 antibodyAnti-MARCH9 antibodyAnti-RNF179 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance