| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MARCH9 (277-346) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MARCHF9 |
| Gene ID: |
92979 |
| Uniprot ID: |
MARH9_HUMAN |
| Immunogen Region: |
277-346 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 277-346 of human MARCH9 (NP_612405.2). |
| Immunogen Sequence: |
GTAGKSGPRNSRTGPTSGAT SRPPAAQRMRTLLPQRCGYT ILHLLGQLRPPDARSSSHSG REVVMRVTTV |
| Tissue Specificity | Ubiquitously expressed. |
| Function | E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I, CD4 and ICAM1, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
| Protein Name | E3 Ubiquitin-Protein Ligase Marchf9Membrane-Associated Ring Finger Protein 9Membrane-Associated Ring-Ch Protein IxMarch-IxRing Finger Protein 179Ring-Type E3 Ubiquitin Transferase Marchf9 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinLysosome Membrane |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Marchf9 antibodyAnti-Membrane-Associated Ring Finger Protein 9 antibodyAnti-Membrane-Associated Ring-Ch Protein Ix antibodyAnti-March-Ix antibodyAnti-Ring Finger Protein 179 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Marchf9 antibodyAnti-MARCHF9 antibodyAnti-MARCH9 antibodyAnti-RNF179 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and CDK7 knockout (KO) 293T cells, using [KO Validated] CDK7 Rabbit polyclonal antibody (STJ114808) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/93895/375110/STJ114808_1__03809.1713141794.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CDK7 knockout (KO) 293T cells, using [KO Validated] CDK7 Rabbit polyclonal antibody (STJ114808) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.")