Anti-MAP7 antibody (8-58) (STJA0006410)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MAP7 AA range: 8-58
General Information
| Short Description | Rabbit polyclonal anti-Ensconsin (8-58) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAP7 |
| Gene ID | 9053 |
| Uniprot ID | MAP7_HUMAN |
| Immunogen | Synthesized peptide derived from human MAP7 AA range: 8-58 |
| Immunogen Region | 8-58 |
| Specificity | This antibody detects endogenous levels of human MAP7 |
Additional Info
| Post Translational Modifications | The association with microtubules is regulated by phosphorylation during the cell cycle. During interphase only phosphorylated on serine. Phosphorylated on threonine in mitosis. |
| Function | Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments. |
| Protein Name | EnsconsinEpithelial Microtubule-Associated Protein Of 115 KdaE-Map-115Microtubule-Associated Protein 7Map-7 |
| Database Links | |
| Cellular Localisation | CytoplasmPerinuclear RegionBasolateral Cell MembraneCytoskeletonColocalized On MicrotubulesAn Intracellular Redistribution Is Triggered During Induction Of Keratinocyte Terminal Differentiation From Microtubules With A Perinuclear Localization To Cortical Microtubules Organized In Spike-Like Bundles Facing Intercellular Contacts |
| Alternative Antibody Names | Anti-Ensconsin antibodyAnti-Epithelial Microtubule-Associated Protein Of 115 Kda antibodyAnti-E-Map-115 antibodyAnti-Microtubule-Associated Protein 7 antibodyAnti-Map-7 antibodyAnti-MAP7 antibody |
Information sourced from Uniprot.org