| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ensconsin (8-58) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAP7 |
| Gene ID: |
9053 |
| Uniprot ID: |
MAP7_HUMAN |
| Immunogen Region: |
8-58 |
| Specificity: |
This antibody detects endogenous levels of human MAP7 |
| Immunogen: |
Synthesized peptide derived from human MAP7 AA range: 8-58 |
| Post Translational Modifications | The association with microtubules is regulated by phosphorylation during the cell cycle. During interphase only phosphorylated on serine. Phosphorylated on threonine in mitosis. |
| Function | Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments. |
| Protein Name | EnsconsinEpithelial Microtubule-Associated Protein Of 115 KdaE-Map-115Microtubule-Associated Protein 7Map-7 |
| Cellular Localisation | CytoplasmPerinuclear RegionBasolateral Cell MembraneCytoskeletonColocalized On MicrotubulesAn Intracellular Redistribution Is Triggered During Induction Of Keratinocyte Terminal Differentiation From Microtubules With A Perinuclear Localization To Cortical Microtubules Organized In Spike-Like Bundles Facing Intercellular Contacts |
| Alternative Antibody Names | Anti-Ensconsin antibodyAnti-Epithelial Microtubule-Associated Protein Of 115 Kda antibodyAnti-E-Map-115 antibodyAnti-Microtubule-Associated Protein 7 antibodyAnti-Map-7 antibodyAnti-MAP7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
