| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MAP3K4 (1-100) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:100-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAP3K4 |
| Gene ID: |
4216 |
| Uniprot ID: |
M3K4_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAP3K4 (NP_005913.2). |
| Immunogen Sequence: |
MREAAAALVPPPAFAVTPAA AMEEPPPPPPPPPPPPEPET ESEPECCLAARQEGTLGDSA CKSPESDLEDFSDETNTENL YGTSPPSTPRQMKRMSTKHQ |
| Tissue Specificity | Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues. |
| Function | Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 4Map Three Kinase 1Mapk/Erk Kinase Kinase 4Mek Kinase 4Mekk 4 |
| Cellular Localisation | CytoplasmPerinuclear RegionLocalized In Perinuclear Vesicular-Like StructuresProbably Golgi-Associated Vesicles |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 antibodyAnti-Map Three Kinase 1 antibodyAnti-Mapk/Erk Kinase Kinase 4 antibodyAnti-Mek Kinase 4 antibodyAnti-Mekk 4 antibodyAnti-MAP3K4 antibodyAnti-KIAA0213 antibodyAnti-MAPKKK4 antibodyAnti-MEKK4 antibodyAnti-MTK1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
