Anti-MAP3K4 antibody (1-100) (STJ11102801)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MAP3K4 (1-100) antibody for use in WB, IHC-P and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:100-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAP3K4 |
| Gene ID | 4216 |
| Uniprot ID | M3K4_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MREAAAALVPPPAFAVTPAA AMEEPPPPPPPPPPPPEPET ESEPECCLAARQEGTLGDSA CKSPESDLEDFSDETNTENL YGTSPPSTPRQMKRMSTKHQ |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAP3K4 (NP_005913.2). |
Additional Info
| Tissue Specificity | Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues. |
| Function | Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 4Map Three Kinase 1Mapk/Erk Kinase Kinase 4Mek Kinase 4Mekk 4 |
| Database Links | |
| Cellular Localisation | CytoplasmPerinuclear RegionLocalized In Perinuclear Vesicular-Like StructuresProbably Golgi-Associated Vesicles |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 antibodyAnti-Map Three Kinase 1 antibodyAnti-Mapk/Erk Kinase Kinase 4 antibodyAnti-Mek Kinase 4 antibodyAnti-Mekk 4 antibodyAnti-MAP3K4 antibodyAnti-KIAA0213 antibodyAnti-MAPKKK4 antibodyAnti-MEKK4 antibodyAnti-MTK1 antibody |
Information sourced from Uniprot.org