Anti-MAN2B1 antibody (640-850) (STJ111978)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MAN2B1 (640-850) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAN2B1 |
| Gene ID | 4125 |
| Uniprot ID | MA2B1_HUMAN |
| Immunogen Region | 640-850 |
| Immunogen Sequence | TFFWYNASIGDNESDQASGA YIFRPNQQKPLPVSRWAQIH LVKTPLVQEVHQNFSAWCSQ VVRLYPGQRHLELEWSVGPI PVGDTWGKEVISRFDTPLET KGRFYTDSNGREILERRRDY RPTWKLNQTEPVAGNYYPVN TRIYITDGNMQLTVLTDRSQ GGSSLRDGSLELMVHRRLLK DDGRGVSEPLMENGSGAWVR GRHLVLLDTAQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 640-850 of human MAN2B1 (NP_000519.2). |
Additional Info
| Post Translational Modifications | First processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). The 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Heavily glycosylated. |
| Function | Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover. Cleaves all known types of alpha-mannosidic linkages. |
| Protein Name | Lysosomal Alpha-MannosidaseLamanLysosomal Acid Alpha-MannosidaseMannosidase Alpha Class 2b Member 1Mannosidase Alpha-B Cleaved Into - Lysosomal Alpha-Mannosidase A Peptide - Lysosomal Alpha-Mannosidase B Peptide - Lysosomal Alpha-Mannosidase C Peptide - Lysosomal Alpha-Mannosidase D Peptide - Lysosomal Alpha-Mannosidase E Peptide |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8853383 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Lysosomal Alpha-Mannosidase antibodyAnti-Laman antibodyAnti-Lysosomal Acid Alpha-Mannosidase antibodyAnti-Mannosidase Alpha Class 2b Member 1 antibodyAnti-Mannosidase Alpha-B Cleaved Into - Lysosomal Alpha-Mannosidase A Peptide - Lysosomal Alpha-Mannosidase B Peptide - Lysosomal Alpha-Mannosidase C Peptide - Lysosomal Alpha-Mannosidase D Peptide - Lysosomal Alpha-Mannosidase E Peptide antibodyAnti-MAN2B1 antibodyAnti-LAMAN antibodyAnti-MANB antibody |
Information sourced from Uniprot.org