Anti-MAGT1 antibody (STJA0006859)

SKU:
STJA0006859

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Magnesium transporter protein 1 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAGT1
Gene ID: 84061
Uniprot ID: MAGT1_HUMAN
Specificity: This antibody detects endogenous levels of MAGT1 at Human, Rat
Immunogen: Synthesized peptide derived from human MAGT1
Function Accessory component of the STT3B-containing form of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues.in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition. May be involved in Mg(2+) transport in epithelial cells.
Protein Name Magnesium Transporter Protein 1
Magt1
Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Magt1
Oligosaccharyl Transferase Subunit Magt1
Implantation-Associated Protein
Iap
Database Links Reactome: R-HSA-446203
Reactome: R-HSA-5223345
Reactome: R-HSA-6798695
Reactome: R-HSA-9694548
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Magnesium Transporter Protein 1 antibody
Anti-Magt1 antibody
Anti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Magt1 antibody
Anti-Oligosaccharyl Transferase Subunit Magt1 antibody
Anti-Implantation-Associated Protein antibody
Anti-Iap antibody
Anti-MAGT1 antibody
Anti-IAG2 antibody
Anti-PSEC0084 antibody
Anti-UNQ628 antibody
Anti-PRO1244 antibody

Information sourced from Uniprot.org

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