Anti-MAGT1 antibody (STJA0006859)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MAGT1
General Information
| Short Description | Rabbit polyclonal anti-Magnesium transporter protein 1 for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAGT1 |
| Gene ID | 84061 |
| Uniprot ID | MAGT1_HUMAN |
| Immunogen | Synthesized peptide derived from human MAGT1 |
| Specificity | This antibody detects endogenous levels of MAGT1 at Human, Rat |
Additional Info
| Function | Accessory component of the STT3B-containing form of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues.in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Also has oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition. Could indirectly play a role in Mg(2+) transport in epithelial cells (Probable). |
| Protein Name | Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Magt1Oligosaccharyl Transferase Subunit Magt1Implantation-Associated ProteinIapMagnesium Transporter Protein 1Magt1 |
| Database Links | Reactome: R-HSA-446203Reactome: R-HSA-5223345Reactome: R-HSA-6798695Reactome: R-HSA-9694548 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndoplasmic ReticulumEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Magt1 antibodyAnti-Oligosaccharyl Transferase Subunit Magt1 antibodyAnti-Implantation-Associated Protein antibodyAnti-Iap antibodyAnti-Magnesium Transporter Protein 1 antibodyAnti-Magt1 antibodyAnti-MAGT1 antibodyAnti-IAG2 antibodyAnti-PSEC0084 antibodyAnti-UNQ628 antibodyAnti-PRO1244 antibody |
Information sourced from Uniprot.org