| Tissue Specificity | Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues. |
| Post Translational Modifications | Phosphorylated by GRK6 upon leukotriene B4 binding.which promotes desensitization. |
| Function | Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. |
| Protein Name | Leukotriene B4 Receptor 1Ltb4-R 1Ltb4-R1Chemoattractant Receptor-Like 1G-Protein Coupled Receptor 16P2y Purinoceptor 7P2y7 |
| Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Leukotriene B4 Receptor 1 antibodyAnti-Ltb4-R 1 antibodyAnti-Ltb4-R1 antibodyAnti-Chemoattractant Receptor-Like 1 antibodyAnti-G-Protein Coupled Receptor 16 antibodyAnti-P2y Purinoceptor 7 antibodyAnti-P2y7 antibodyAnti-LTB4R antibodyAnti-BLT antibodyAnti-BLT1 antibodyAnti-BLTR antibodyAnti-CMKRL1 antibodyAnti-GPR16 antibodyAnti-P2RY7 antibody |
Information sourced from Uniprot.org
