| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LRRC4 (450-500 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
LRRC4 |
| Gene ID: |
64101 |
| Uniprot ID: |
LRRC4_HUMAN |
| Immunogen Region: |
450-500 aa |
| Specificity: |
Specific for LRRC4. |
| Immunogen: |
A synthetic peptide from aa region 450-500 of human LRRC4 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 97% identity with rat and mouse sequences. |
| Post Translational Modifications | N-glycosylated. |
| Function | Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays an important role for auditory synaptic responses. Involved in the suppression of glioma. |
| Protein Name | Leucine-Rich Repeat-Containing Protein 4Brain Tumor-Associated Protein BagNasopharyngeal Carcinoma-Associated Gene 14 ProteinNetrin-G2 LigandNgl-2 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinPostsynaptic Cell MembraneLrrc4 And Dlg4 Are Interdependent For Synaptic Localization |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat-Containing Protein 4 antibodyAnti-Brain Tumor-Associated Protein Bag antibodyAnti-Nasopharyngeal Carcinoma-Associated Gene 14 Protein antibodyAnti-Netrin-G2 Ligand antibodyAnti-Ngl-2 antibodyAnti-LRRC4 antibodyAnti-BAG antibodyAnti-NAG14 antibodyAnti-UNQ554 antibodyAnti-PRO1111 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
