Anti-LRRC4 antibody (450-500 aa) (STJ13101329)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 450-500 of human LRRC4 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 97% identity with rat and mouse sequences.
General Information
| Short Description | Rabbit polyclonal anti-LRRC4 (450-500 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | LRRC4 |
| Gene ID | 64101 |
| Uniprot ID | LRRC4_HUMAN |
| Immunogen | A synthetic peptide from aa region 450-500 of human LRRC4 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 97% identity with rat and mouse sequences. |
| Immunogen Region | 450-500 aa |
| Specificity | Specific for LRRC4. |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays an important role for auditory synaptic responses. Involved in the suppression of glioma. |
| Protein Name | Leucine-Rich Repeat-Containing Protein 4Brain Tumor-Associated Protein BagNasopharyngeal Carcinoma-Associated Gene 14 ProteinNetrin-G2 LigandNgl-2 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinPostsynaptic Cell MembraneLrrc4 And Dlg4 Are Interdependent For Synaptic Localization |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat-Containing Protein 4 antibodyAnti-Brain Tumor-Associated Protein Bag antibodyAnti-Nasopharyngeal Carcinoma-Associated Gene 14 Protein antibodyAnti-Netrin-G2 Ligand antibodyAnti-Ngl-2 antibodyAnti-LRRC4 antibodyAnti-BAG antibodyAnti-NAG14 antibodyAnti-UNQ554 antibodyAnti-PRO1111 antibody |
Information sourced from Uniprot.org