Anti-LRIT3 antibody (156-206 aa) (STJ197620)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human LRIT3 at the amino acid range 156-206
General Information
| Short Description | Rabbit polyclonal anti-Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (156-206 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LRIT3 |
| Gene ID | 345193 |
| Uniprot ID | LRIT3_HUMAN |
| Immunogen | Synthesized peptide derived from the human LRIT3 at the amino acid range 156-206 |
| Immunogen Region | 156-206 aa |
| Specificity | This antibody detects endogenous levels of human LRIT3 |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Plays a role in the synapse formation and synaptic transmission between cone photoreceptor cells and retinal bipolar cells. Required for normal transmission of a light-evoked stimulus from the cone photoreceptor cells to the ON-bipolar cells and ON-ganglion cells in the inner retina. Required in retinal ON-bipolar cells for normal localization of the cation channel TRPM1 at dendrite tips. Seems to play a specific role in synaptic contacts made by ON-bipolar cells with cone photoreceptor pedicles. May also have a role in cone synapse formation. Might facilitate FGFR1 exit from the endoplasmic reticulum to the Golgi. Could be a regulator of the FGFRs. |
| Protein Name | Leucine-Rich Repeat - Immunoglobulin-Like Domain And Transmembrane Domain-Containing Protein 3 |
| Database Links | |
| Cellular Localisation | Cell ProjectionDendritePerikaryonEndoplasmic Reticulum MembraneSingle-Pass Type I Membrane ProteinPunctate Expression At Dendrite Tips |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat - Immunoglobulin-Like Domain And Transmembrane Domain-Containing Protein 3 antibodyAnti-LRIT3 antibody |
Information sourced from Uniprot.org