| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (156-206 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LRIT3 |
| Gene ID: |
345193 |
| Uniprot ID: |
LRIT3_HUMAN |
| Immunogen Region: |
156-206 aa |
| Specificity: |
This antibody detects endogenous levels of human LRIT3 |
| Immunogen: |
Synthesized peptide derived from the human LRIT3 at the amino acid range 156-206 |
| Post Translational Modifications | Glycosylated. |
| Function | Plays a role in the synapse formation and synaptic transmission between cone photoreceptor cells and retinal bipolar cells. Required for normal transmission of a light-evoked stimulus from the cone photoreceptor cells to the ON-bipolar cells and ON-ganglion cells in the inner retina. Required in retinal ON-bipolar cells for normal localization of the cation channel TRPM1 at dendrite tips. Seems to play a specific role in synaptic contacts made by ON-bipolar cells with cone photoreceptor pedicles. May also have a role in cone synapse formation. Might facilitate FGFR1 exit from the endoplasmic reticulum to the Golgi. Could be a regulator of the FGFRs. |
| Protein Name | Leucine-Rich Repeat - Immunoglobulin-Like Domain And Transmembrane Domain-Containing Protein 3 |
| Cellular Localisation | Cell ProjectionDendritePerikaryonEndoplasmic Reticulum MembraneSingle-Pass Type I Membrane ProteinPunctate Expression At Dendrite Tips |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat - Immunoglobulin-Like Domain And Transmembrane Domain-Containing Protein 3 antibodyAnti-LRIT3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
