| Host: |
Rabbit |
| Applications: |
WB/IF/ELISA |
| Reactivity: |
Human/Mouse/Monkey |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Lysophosphatidic acid receptor 2 (271-320 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IF 1:200-1:1000ELISA 1:40000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LPAR2Uniprot ID=LPAR2_HUMAN" |
| Immunogen Region: |
271-320 aa |
| Specificity: |
EDG-4 Polyclonal Antibody detects endogenous levels of EDG-4 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human EDG4 at the amino acid range 271-320 |
| Function | Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation. |
| Protein Name | Lysophosphatidic Acid Receptor 2Lpa Receptor 2Lpa-2Lysophosphatidic Acid Receptor Edg-4 |
| Cellular Localisation | Cell SurfaceCell MembraneMulti-Pass Membrane ProteinPrior To Lpa Treatment Found Predominantly At The Cell Surface But In The Presence Of Lpa Colocalizes With Rala In The Endocytic Vesicles |
| Alternative Antibody Names | Anti-Lysophosphatidic Acid Receptor 2 antibodyAnti-Lpa Receptor 2 antibodyAnti-Lpa-2 antibodyAnti-Lysophosphatidic Acid Receptor Edg-4 antibodyAnti-LPAR2 antibodyAnti-EDG4 antibodyAnti-LPA2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
