Anti-LPAR2 antibody (271-320 aa) (STJ92829)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human EDG4 at the amino acid range 271-320
General Information
| Short Description | Rabbit polyclonal anti-Lysophosphatidic acid receptor 2 (271-320 aa) for use in WB, IF and ELISA in Human, Mouse and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LPAR2 |
| Gene ID | 9170 |
| Uniprot ID | LPAR2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human EDG4 at the amino acid range 271-320 |
| Immunogen Region | 271-320 aa |
| Specificity | EDG-4 Polyclonal Antibody detects endogenous levels of EDG-4 protein. |
Additional Info
| Function | Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation. |
| Protein Name | Lysophosphatidic Acid Receptor 2Lpa Receptor 2Lpa-2Lysophosphatidic Acid Receptor Edg-4 |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-418594Reactome: R-HSA-419408 |
| Cellular Localisation | Cell SurfaceCell MembraneMulti-Pass Membrane ProteinPrior To Lpa Treatment Found Predominantly At The Cell Surface But In The Presence Of Lpa Colocalizes With Rala In The Endocytic Vesicles |
| Alternative Antibody Names | Anti-Lysophosphatidic Acid Receptor 2 antibodyAnti-Lpa Receptor 2 antibodyAnti-Lpa-2 antibodyAnti-Lysophosphatidic Acid Receptor Edg-4 antibodyAnti-LPAR2 antibodyAnti-EDG4 antibodyAnti-LPA2 antibody |
Information sourced from Uniprot.org