| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Protein LMBR1L (220-270 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LMBR1L |
| Gene ID: |
55716 |
| Uniprot ID: |
LMBRL_HUMAN |
| Immunogen Region: |
220-270 aa |
| Specificity: |
This antibody detects endogenous levels of LMBRL at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human LMBRL at the amino acid range 220-270 |
| Function | Plays an essential role in lymphocyte development by negatively regulating the canonical Wnt signaling pathway. In association with UBAC2 and E3 ubiquitin-protein ligase AMFR, promotes the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6. LMBR1L stabilizes the beta-catenin destruction complex that is required for regulating CTNNB1 levels. Acts as a LCN1 receptor and can mediate its endocytosis. |
| Protein Name | Protein Lmbr1lLimb Region 1 Protein Homolog-LikeLipocalin-1-Interacting Membrane ReceptorLimr |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Protein Lmbr1l antibodyAnti-Limb Region 1 Protein Homolog-Like antibodyAnti-Lipocalin-1-Interacting Membrane Receptor antibodyAnti-Limr antibodyAnti-LMBR1L antibodyAnti-KIAA1174 antibodyAnti-LIMR antibodyAnti-UNQ458 antibodyAnti-PRO783 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
