Anti-LMAN1 antibody (270-480) (STJ112470)

Name: Anti-LMAN1 antibody (270-480) (STJ112470)
SKU: STJ112470
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ112470

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Short Description	Rabbit polyclonal LMAN1 (270-480) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:50-1:100 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	LMAN1
Gene ID	3998
Uniprot ID	LMAN1_HUMAN
Immunogen Region	270-480
Immunogen Sequence	PGKEPPTPDKEISEKEKEKY QEEFEHFQQELDKKKEEFQK GHPDLQGQPAEEIFESVGDR ELRQVFEGQNRIHLEIKQLN RQLDMILDEQRRYVSSLTEE ISKRGAGMPGQHGQITQQEL DTVVKTQHEILRQVNEMKNS MSETVRLVSGMQHPGSAGGV YETTQHFIDIKEHLHIVKRD IDNLVQRNMPSNEKPKCPEL PPFPSCLSTVH
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 270-480 of human LMAN1 (NP_005561.1).

Tissue Specificity	Ubiquitous.
Post Translational Modifications	The N-terminal may be partly blocked.
Function	Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.
Protein Name	Protein Ergic-53 Er-Golgi Intermediate Compartment 53 Kda Protein Gp58 Intracellular Mannose-Specific Lectin Mr60 Lectin Mannose-Binding 1
Database Links	Reactome: R-HSA-204005 Reactome: R-HSA-5694530 Reactome: R-HSA-8980692 Reactome: R-HSA-9013106 Reactome: R-HSA-9013404 Reactome: R-HSA-9013405 Reactome: R-HSA-9013408 Reactome: R-HSA-9013423 Reactome: R-HSA-948021
Cellular Localisation	Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Single-Pass Type I Membrane Protein Golgi Apparatus Membrane Single-Pass Membrane Protein Endoplasmic Reticulum Membrane
Alternative Antibody Names	Anti-Protein Ergic-53 antibody Anti-Er-Golgi Intermediate Compartment 53 Kda Protein antibody Anti-Gp58 antibody Anti-Intracellular Mannose-Specific Lectin Mr60 antibody Anti-Lectin Mannose-Binding 1 antibody Anti-LMAN1 antibody Anti-ERGIC53 antibody Anti-F5F8D antibody

Information sourced from Uniprot.org