| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LIMCH1 (150-450) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LIMCH1 |
| Gene ID: |
22998 |
| Uniprot ID: |
LIMC1_HUMAN |
| Immunogen Region: |
150-450 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 150-450 of human LIMCH1 (NP_001106189.1). |
| Immunogen Sequence: |
LKEFEGLLAQMRKDTDDIES PKRSIRDSGYIDCWDSERSD SLSPPRHGRDDSFDSLDSFG SRSRQTPSPDVVLRGSSDGR GSDSESDLPHRKLPDVKKDD MSARRTSHGEPKSAVPFNQY LPNKSNQTAYVPAPLRKKKA EREEYRKSWSTATSPLGGER PFRYGPRTPVSDDAESTSMF DMRCEEEAAVQPHSRARQEQ LQLINNQLREEDDKWQDDLA RWKSRRRSVSQDLIKKEEE |
| Function | Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration. |
| Protein Name | Lim And Calponin Homology Domains-Containing Protein 1 |
| Cellular Localisation | CytoplasmCytoskeletonStress Fiber |
| Alternative Antibody Names | Anti-Lim And Calponin Homology Domains-Containing Protein 1 antibodyAnti-LIMCH1 antibodyAnti-KIAA1102 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
