| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Mitochondrial proton/calcium exchanger protein/H+exchanger (574-624 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LETM1 |
| Gene ID: |
3954 |
| Uniprot ID: |
LETM1_HUMAN |
| Immunogen Region: |
574-624 aa |
| Specificity: |
This antibody detects endogenous levels of LETM1 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human LETM1 at the amino acid range 574-624 |
| Function | Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport. Mediates proton-dependent calcium efflux from mitochondrion. Functions also as an electroneutral mitochondrial proton/potassium exchanger. Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization. |
| Protein Name | Mitochondrial Proton/Calcium Exchanger ProteinElectroneutral Mitochondrial K(+/H(+ExchangerKheLeucine Zipper-Ef-Hand-Containing Transmembrane Protein 1 |
| Database Links | Reactome: R-HSA-8949215Reactome: R-HSA-9013408 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Proton/Calcium Exchanger Protein antibodyAnti-Electroneutral Mitochondrial K(+/H(+Exchanger antibodyAnti-Khe antibodyAnti-Leucine Zipper-Ef-Hand-Containing Transmembrane Protein 1 antibodyAnti-LETM1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
