Anti-LETM1 antibody (574-624 aa) (STJ194216)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human LETM1 at the amino acid range 574-624
General Information
| Short Description | Rabbit polyclonal anti-Mitochondrial proton/calcium exchanger protein/H+exchanger (574-624 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LETM1 |
| Gene ID | 3954 |
| Uniprot ID | LETM1_HUMAN |
| Immunogen | Synthesized peptide derived from the human LETM1 at the amino acid range 574-624 |
| Immunogen Region | 574-624 aa |
| Specificity | This antibody detects endogenous levels of LETM1 at Human/Mouse/Rat |
Additional Info
| Function | Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport. Mediates proton-dependent calcium efflux from mitochondrion. Also functions as an electroneutral mitochondrial proton/potassium exchanger. Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization. |
| Protein Name | Mitochondrial Proton/Calcium Exchanger ProteinElectroneutral Mitochondrial K(+/H(+ExchangerKheLeucine Zipper-Ef-Hand-Containing Transmembrane Protein 1 |
| Database Links | Reactome: R-HSA-8949215Reactome: R-HSA-9013408Reactome: R-HSA-9865881 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Proton/Calcium Exchanger Protein antibodyAnti-Electroneutral Mitochondrial K(+/H(+Exchanger antibodyAnti-Khe antibodyAnti-Leucine Zipper-Ef-Hand-Containing Transmembrane Protein 1 antibodyAnti-LETM1 antibody |
Information sourced from Uniprot.org