| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LEPRE1 (497-736) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
P3H1 |
| Gene ID: |
64175 |
| Uniprot ID: |
P3H1_HUMAN |
| Immunogen Region: |
497-736 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 497-736 of human LEPRE1 (NP_071751.3). |
| Immunogen Sequence: |
GDGYRGQTSPHTPNEKFYGV TVFKALKLGQEGKVPLQSAH LYYNVTEKVRRIMESYFRLD TPLYFSYSHLVCRTAIEEVQ AERKDDSHPVHVDNCILNAE TLVCVKEPPAYTFRDYSAIL YLNGDFDGGNFYFTELDAKT VTAEVQPQCGRAVGFSSGTE NPHGVKAVTRGQRCAIALWF TLDPRHSERDRVQADDLVKM LFSPEEMDLSQEQPLDAQQG PPEPAQESLSGSESKPKDE |
| Post Translational Modifications | O-glycosylated.chondroitin sulfate. |
| Function | Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts. |
| Protein Name | Prolyl 3-Hydroxylase 1Growth Suppressor 1Leucine- And Proline-Enriched Proteoglycan 1Leprecan-1 |
| Database Links | Reactome: R-HSA-1650814 |
| Cellular Localisation | Isoform 1: Endoplasmic ReticulumSecretedExtracellular SpaceExtracellular MatrixSecreted Into The Extracellular Matrix As A Chondroitin Sulfate Proteoglycan (Cspg) |
| Alternative Antibody Names | Anti-Prolyl 3-Hydroxylase 1 antibodyAnti-Growth Suppressor 1 antibodyAnti-Leucine- And Proline-Enriched Proteoglycan 1 antibodyAnti-Leprecan-1 antibodyAnti-P3H1 antibodyAnti-GROS1 antibodyAnti-LEPRE1 antibodyAnti-PSEC0109 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
