Anti-LDB3 antibody (1-283) (STJ29598)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LDB3 (1-283) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LDB3 |
| Gene ID | 11155 |
| Uniprot ID | LDB3_HUMAN |
| Immunogen Region | 1-283 |
| Immunogen Sequence | MSYSVTLTGPGPWGFRLQGG KDFNMPLTISRITPGSKAAQ SQLSQGDLVVAIDGVNTDTM THLEAQNKIKSASYNLSLTL QKSKRPIPISTTAPPVQTPL PVIPHQKVVVNSPANADYQE RFNPSALKDSALSTHKPIEV KGLGGKATIIHAQYNTPISM YSQDAIMDAIAGQAQAQGSD FSGSLPIKDLAVDSASPVYQ AVIKSQNKPEDEADEWARRS SNLQSRSFRILAQMTGTEF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human LDB3 (NP_001073585.1). |
Additional Info
| Tissue Specificity | Expressed primarily in skeletal muscle and to a lesser extent in heart. Also detected in brain and placenta. |
| Function | May function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton. |
| Protein Name | Lim Domain-Binding Protein 3Protein CypherZ-Band Alternatively Spliced Pdz-Motif Protein |
| Database Links | |
| Cellular Localisation | CytoplasmPerinuclear RegionCell ProjectionPseudopodiumCytoskeletonMyofibrilSarcomereZ LineLocalized To The Cytoplasm Around Nuclei And Pseudopodia Of Undifferentiated Cells And Detected Throughout The Myotubes Of Differentiated CellsColocalizes With Actn2 At The Z-Lines |
| Alternative Antibody Names | Anti-Lim Domain-Binding Protein 3 antibodyAnti-Protein Cypher antibodyAnti-Z-Band Alternatively Spliced Pdz-Motif Protein antibodyAnti-LDB3 antibodyAnti-KIAA0613 antibodyAnti-ZASP antibody |
Information sourced from Uniprot.org