Anti-KYNU antibody (1-465) [S5268RM] (STJ11105268)

Name: Anti-KYNU antibody (1-465) [S5268RM] (STJ11105268)
SKU: STJ11105268
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11105268

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Short Description	Rabbit monoclonal Kynureninase (1-465) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S5268RM
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	KYNU
Gene ID	8942
Uniprot ID	KYNU_HUMAN
Immunogen Region	1-465
Immunogen Sequence	MEPSSLELPADTVQRIAAEL KCHPTDERVALHLDEEDKLR HFRECFYIPKIQDLPPVDLS LVNKDENAIYFLGNSLGLQP KMVKTYLEEELDKWAKIAAY GHEVGKRPWITGDESIVGLM KDIVGANEKEIALMNALTVN LHLLMLSFFKPTPKRYKILL EAKAFPSDHYAIESQLQLHG LNIEESMRMIKPREGEETLR IEDILEVIEKEGDSIAVILF SGVHFYTGQHFNIPAITKA
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-465 of human KYNU (NP_003928.1).

Tissue Specificity	Expressed in all tissues tested (heart, brain placenta, lung, liver, skeletal muscle, kidney and pancreas). Highest levels found in placenta, liver and lung. Expressed in all brain regions.
Function	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
Protein Name	Kynureninase L-Kynurenine Hydrolase
Database Links	Reactome: R-HSA-71240
Cellular Localisation	Cytoplasm Cytosol
Alternative Antibody Names	Anti-Kynureninase antibody Anti-L-Kynurenine Hydrolase antibody Anti-KYNU antibody

Information sourced from Uniprot.org