• Western blot analysis of various lysates, using KYNU Rabbit monoclonal antibody (STJ11105268) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
  • Western blot analysis of various lysates, using KYNU Rabbit monoclonal antibody (STJ11105268) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-KYNU antibody (1-465) [S5268RM] (STJ11105268)

SKU:
STJ11105268

£146.50 - £639.50
Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Kynureninase (1-465) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S5268RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KYNU
Gene ID: 8942
Uniprot ID: KYNU_HUMAN
Immunogen Region: 1-465
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-465 of human KYNU (NP_003928.1).
Immunogen Sequence: MEPSSLELPADTVQRIAAEL KCHPTDERVALHLDEEDKLR HFRECFYIPKIQDLPPVDLS LVNKDENAIYFLGNSLGLQP KMVKTYLEEELDKWAKIAAY GHEVGKRPWITGDESIVGLM KDIVGANEKEIALMNALTVN LHLLMLSFFKPTPKRYKILL EAKAFPSDHYAIESQLQLHG LNIEESMRMIKPREGEETLR IEDILEVIEKEGDSIAVILF SGVHFYTGQHFNIPAITKA
Tissue Specificity Expressed in all tissues tested (heart, brain placenta, lung, liver, skeletal muscle, kidney and pancreas). Highest levels found in placenta, liver and lung. Expressed in all brain regions.
Function Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
Protein Name Kynureninase
L-Kynurenine Hydrolase
Database Links Reactome: R-HSA-71240
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Kynureninase antibody
Anti-L-Kynurenine Hydrolase antibody
Anti-KYNU antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance