| Host: |
Rabbit |
| Applications: |
IHC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Keratin-Type Ii Cytoskeletal 73 is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: |
Antigen affinity purification |
| Concentration: |
0.9 mg/mL |
| Dilution Range: |
IHC 1:40-1:200 |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Tissue Specificity | Highly expressed in hair follicles from scalp. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, it is expressed between the lowermost bulb region of the cuticle and the region where Henle cells undergo abrupt terminal differentiation. Detected up to the uppermost cortex region where cuticle cells terminally differentiate (at protein level). |
| Function | Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). |
| Protein Name | Keratin - Type Ii Cytoskeletal 73Cytokeratin-73Ck-73Keratin-73K73Type Ii Inner Root Sheath-Specific Keratin-K6irs3Type-Ii Keratin Kb36 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 73 antibodyAnti-Cytokeratin-73 antibodyAnti-Ck-73 antibodyAnti-Keratin-73 antibodyAnti-K73 antibodyAnti-Type Ii Inner Root Sheath-Specific Keratin-K6irs3 antibodyAnti-Type-Ii Keratin Kb36 antibodyAnti-KRT73 antibodyAnti-K6IRS3 antibodyAnti-KB36 antibodyAnti-KRT6IRS3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
