| Host: | Rabbit |
| Applications: | IHC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Keratin-Type Ii Cytoskeletal 73 is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: | Antigen affinity purification |
| Concentration: | 0.9 mg/mL |
| Dilution Range: | IHC 1:40-1:200 |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Gene Symbol: | KRT73 |
| Gene ID: | 319101 |
| Uniprot ID: | K2C73_HUMAN |
| Immunogen: | Full length fusion protein |
| Tissue Specificity | Highly expressed in hair follicles from scalp. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, it is expressed between the lowermost bulb region of the cuticle and the region where Henle cells undergo abrupt terminal differentiation. Detected up to the uppermost cortex region where cuticle cells terminally differentiate (at protein level). |
| Function | Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). |
| Protein Name | Keratin - Type Ii Cytoskeletal 73 Cytokeratin-73 Ck-73 Keratin-73 K73 Type Ii Inner Root Sheath-Specific Keratin-K6irs3 Type-Ii Keratin Kb36 |
| Database Links | Reactome: R-HSA-6805567 Reactome: R-HSA-6809371 |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 73 antibody Anti-Cytokeratin-73 antibody Anti-Ck-73 antibody Anti-Keratin-73 antibody Anti-K73 antibody Anti-Type Ii Inner Root Sheath-Specific Keratin-K6irs3 antibody Anti-Type-Ii Keratin Kb36 antibody Anti-KRT73 antibody Anti-K6IRS3 antibody Anti-KB36 antibody Anti-KRT6IRS3 antibody |
Information sourced from Uniprot.org