| Host: |
Mouse |
| Applications: |
IHC/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Keratin, type II cytoskeletal 7 (350-469 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
ABT436 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1k |
| Formulation: |
Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein. |
| Purification: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: |
IHC-P 1:200-400WB 500-1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KRT7 |
| Gene ID: |
3855 |
| Uniprot ID: |
K2C7_HUMAN |
| Immunogen Region: |
350-469 aa |
| Specificity: |
The antibody can specifically recognize human CK7 protein, and shows no cross reaction with CK1, 4, 5, 6, 8, 10, 14, 17, 18, 19, 20. In western blotting of Hela, A431, A549 and Hela cell lysates, the |
| Immunogen: |
Synthesized peptide derived from the human Cytokeratin 7 at the amino acid range 350-469 |
| Post Translational Modifications | Arg-20 is dimethylated, probably to asymmetric dimethylarginine. |
| Function | Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). |
| Protein Name | Keratin - Type Ii Cytoskeletal 7Cytokeratin-7Ck-7Keratin-7K7SarcolectinType-Ii Keratin Kb7 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 7 antibodyAnti-Cytokeratin-7 antibodyAnti-Ck-7 antibodyAnti-Keratin-7 antibodyAnti-K7 antibodyAnti-Sarcolectin antibodyAnti-Type-Ii Keratin Kb7 antibodyAnti-KRT7 antibodyAnti-SCL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
