Anti-KRT7 antibody (350-469 aa) [ABT436] (STJ190054)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenSynthesized peptide derived from the human Cytokeratin 7 at the amino acid range 350-469
General Information
| Short Description | Mouse monoclonal anti-Keratin, type II cytoskeletal 7 (350-469 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ABT436 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC-P 1:200-400WB 500-1000 |
| Formulation | Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRT7 |
| Gene ID | 3855 |
| Uniprot ID | K2C7_HUMAN |
| Immunogen | Synthesized peptide derived from the human Cytokeratin 7 at the amino acid range 350-469 |
| Immunogen Region | 350-469 aa |
| Specificity | The antibody can specifically recognize human CK7 protein, and shows no cross reaction with CK1, 4, 5, 6, 8, 10, 14, 17, 18, 19, 20. In western blotting of Hela, A431, A549 and Hela cell lysates, the |
Additional Info
| Post Translational Modifications | Arg-20 is dimethylated, probably to asymmetric dimethylarginine. |
| Function | Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). |
| Protein Name | Keratin - Type Ii Cytoskeletal 7Cytokeratin-7Ck-7Keratin-7K7SarcolectinType-Ii Keratin Kb7 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 7 antibodyAnti-Cytokeratin-7 antibodyAnti-Ck-7 antibodyAnti-Keratin-7 antibodyAnti-K7 antibodyAnti-Sarcolectin antibodyAnti-Type-Ii Keratin Kb7 antibodyAnti-KRT7 antibodyAnti-SCL antibody |
Information sourced from Uniprot.org