Anti-KRT4 antibody (1-100) [S1MR] (STJ11101221)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Cytokeratin 4 (1-100) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S1MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000IHC-P:1:500-1:2000IF/ICC:1:100-1:400ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRT4 |
| Gene ID | 3851 |
| Uniprot ID | K2C4_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MIARQQCVRGGPRGFSCGSA IVGGGKRGAFSSVSMSGGAG RCSSGGFGSRSLYNLRGNKS ISMSVAGSRQGACFGGAGGF GTGGFGGGFGGSFSGKGGPG |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cytokeratin 4 (KRT4) (P19013). |
Additional Info
| Tissue Specificity | Detected in the suprabasal layer of the stratified epithelium of the esophagus, exocervix, vagina, mouth and lingual mucosa, and in cells and cell clusters in the mucosa and serous gland ducts of the esophageal submucosa (at protein level). Expressed widely in the exocervix and esophageal epithelium, with lowest levels detected in the basal cell layer. |
| Protein Name | Keratin - Type Ii Cytoskeletal 4Cytokeratin-4Ck-4Keratin-4K4Type-Ii Keratin Kb4 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 4 antibodyAnti-Cytokeratin-4 antibodyAnti-Ck-4 antibodyAnti-Keratin-4 antibodyAnti-K4 antibodyAnti-Type-Ii Keratin Kb4 antibodyAnti-KRT4 antibodyAnti-CYK4 antibody |
Information sourced from Uniprot.org