• Immunohistochemistry analysis of paraffin-embedded human placenta using KLKB1 antibody (STJ27271) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of Mouse plasma, using KLKB1 antibody (STJ27271) at 1:600 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 120s.

Anti-KLKB1 antibody (20-300) (STJ27271)

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STJ27271

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-KLKB1 (20-300) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KLKB1
Gene ID: 3818
Uniprot ID: KLKB1_HUMAN
Immunogen Region: 20-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human KLKB1 (NP_000883.2).
Immunogen Sequence: GCLTQLYENAFFRGGDVASM YTPNAQYCQMRCTFHPRCLL FSFLPASSINDMEKRFGCFL KDSVTGTLPKVHRTGAVSGH SLKQCGHQISACHRDIYKGV DMRGVNFNVSKVSSVEECQK RCTSNIRCQFFSYATQTFHK AEYRNNCLLKYSPGGTPTAI KVLSNVESGFSLKPCALSEI GCHMNIFQHLAFSDVDVARV LTPDAFVCRTICTYHPNCLF FTFYTNVWKIESQRNVCLL
Function The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Protein Name Plasma Kallikrein
Fletcher Factor
Kininogenin
Plasma Prekallikrein
Pkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain
Database Links Reactome: R-HSA-140837
Reactome: R-HSA-1592389
Reactome: R-HSA-9657688
Reactome: R-HSA-9657689
Cellular Localisation Secreted
Alternative Antibody Names Anti-Plasma Kallikrein antibody
Anti-Fletcher Factor antibody
Anti-Kininogenin antibody
Anti-Plasma Prekallikrein antibody
Anti-Pkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain antibody
Anti-KLKB1 antibody
Anti-KLK3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance