Anti-KLF17 antibody (210-389) (STJ115694)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal KLF17 (210-389) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KLF17 |
| Gene ID | 128209 |
| Uniprot ID | KLF17_HUMAN |
| Immunogen Region | 210-389 |
| Immunogen Sequence | QMLPPQDAHDLGMPPAESQS LLVLGSQDSLVSQPDSQEGP FLPEQPGPAPQTVEKNSRPQ EGTGRRGSSEARPYCCNYEN CGKAYTKRSHLVSHQRKHTG ERPYSCNWESCSWSFFRSDE LRRHMRVHTRYRPYKCDQCS REFMRSDHLKQHQKTHRPGP SDPQANNNNGEQDSPPAAGP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 210-389 of human KLF17 (NP_775755.3). |
Additional Info
| Function | Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development. |
| Protein Name | Krueppel-Like Factor 17Zinc Finger Protein 393 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 17 antibodyAnti-Zinc Finger Protein 393 antibodyAnti-KLF17 antibodyAnti-ZNF393 antibody |
Information sourced from Uniprot.org