| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KIR3DS1 (80-340) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIR3DS1 |
| Gene ID: |
3813 |
| Uniprot ID: |
KI3S1_HUMAN |
| Immunogen Region: |
80-340 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human KIR3DS1 (NP_001077008.1). |
| Immunogen Sequence: |
FNMSPVTTAHAGNYTCRGSH PHSPTGWSAPSNPMVIMVTG NHRKPSLLAHPGPLVKSGER VILQCWSDIMFEHFFLHKEW ISKDPSRLVGQIHDGVSKAN FSIGSMMRALAGTYRCYGSV THTPYQLSAPSDPLDIVVTG LYEKPSLSAQPGPKVQAGES VTLSCSSRSSYDMYHLSREG GAHERRLPAVRKVNRTFQAD FPLGPATHGGTYRCFGSFRH SPYEWSDPSDPLLVSVTGN |
| Tissue Specificity | Expressed in NK and T-cell lines but not in B-lymphoblastoid cell lines or in a colon carcinoma cell line. |
| Function | Receptor on natural killer (NK) cells for MHC class I molecules. Upon interaction with peptide-free HLA-F open conformer, triggers NK cell degranulation and anti-viral cytokine production. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 3ds1Natural Killer-Associated Transcript 10Nkat-10 |
| Database Links | Reactome: R-HSA-2172127 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 3ds1 antibodyAnti-Natural Killer-Associated Transcript 10 antibodyAnti-Nkat-10 antibodyAnti-KIR3DS1 antibodyAnti-NKAT10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and EIF3H knockout (KO) HeLa cells, using [KO Validated] EIF3H Rabbit polyclonal antibody (STJ119999) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98784/382834/STJ119999_1__50326.1713151342.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and EIF3H knockout (KO) HeLa cells, using [KO Validated] EIF3H Rabbit polyclonal antibody (STJ119999) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.")
