Anti-KIR3DS1 antibody (80-340) (STJ111977)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal KIR3DS1 (80-340) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KIR3DS1 |
| Gene ID | 3813 |
| Uniprot ID | KI3S1_HUMAN |
| Immunogen Region | 80-340 |
| Immunogen Sequence | FNMSPVTTAHAGNYTCRGSH PHSPTGWSAPSNPMVIMVTG NHRKPSLLAHPGPLVKSGER VILQCWSDIMFEHFFLHKEW ISKDPSRLVGQIHDGVSKAN FSIGSMMRALAGTYRCYGSV THTPYQLSAPSDPLDIVVTG LYEKPSLSAQPGPKVQAGES VTLSCSSRSSYDMYHLSREG GAHERRLPAVRKVNRTFQAD FPLGPATHGGTYRCFGSFRH SPYEWSDPSDPLLVSVTGN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human KIR3DS1 (NP_001077008.1). |
Additional Info
| Tissue Specificity | Expressed in NK and T-cell lines but not in B-lymphoblastoid cell lines or in a colon carcinoma cell line. |
| Function | Receptor on natural killer (NK) cells for MHC class I molecules. Upon interaction with peptide-free HLA-F open conformer, triggers NK cell degranulation and anti-viral cytokine production. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 3ds1Natural Killer-Associated Transcript 10Nkat-10 |
| Database Links | Reactome: R-HSA-2172127 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 3ds1 antibodyAnti-Natural Killer-Associated Transcript 10 antibodyAnti-Nkat-10 antibodyAnti-KIR3DS1 antibodyAnti-NKAT10 antibody |
Information sourced from Uniprot.org