| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Kinesin-like protein KIF23 is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KIF23 |
| Gene ID: | 9493 |
| Uniprot ID: | KIF23_HUMAN |
| Specificity: | KIF23 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | Ubiquitinated. Deubiquitinated by USP8/UBPY. |
| Function | Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. |
| Protein Name | Kinesin-Like Protein Kif23 Kinesin-Like Protein 5 Mitotic Kinesin-Like Protein 1 |
| Database Links | Reactome: R-HSA-2132295 Reactome: R-HSA-6811434 Reactome: R-HSA-68884 Reactome: R-HSA-983189 |
| Cellular Localisation | Nucleus Cytoplasm Cytoskeleton Spindle Midbody Midbody Ring Localizes To The Interzone Of Mitotic Spindles Detected At The Midbody During Later Stages Of Mitotic Cytokinesis |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif23 antibody Anti-Kinesin-Like Protein 5 antibody Anti-Mitotic Kinesin-Like Protein 1 antibody Anti-KIF23 antibody Anti-KNSL5 antibody Anti-MKLP1 antibody |
Information sourced from Uniprot.org