Anti-KIF23 antibody (STJ191905)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Kinesin-like protein KIF23 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KIF23 |
| Gene ID | 9493 |
| Uniprot ID | KIF23_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | KIF23 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Ubiquitinated. Deubiquitinated by USP8/UBPY. |
| Function | Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. |
| Protein Name | Kinesin-Like Protein Kif23Kinesin-Like Protein 5Mitotic Kinesin-Like Protein 1 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-6811434Reactome: R-HSA-68884Reactome: R-HSA-983189 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonSpindleMidbodyMidbody RingLocalizes To The Interzone Of Mitotic SpindlesDetected At The Midbody During Later Stages Of Mitotic Cytokinesis |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif23 antibodyAnti-Kinesin-Like Protein 5 antibodyAnti-Mitotic Kinesin-Like Protein 1 antibodyAnti-KIF23 antibodyAnti-KNSL5 antibodyAnti-MKLP1 antibody |
Information sourced from Uniprot.org