| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KIF13A (1300-1600) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIF13A |
| Gene ID: |
63971 |
| Uniprot ID: |
KI13A_HUMAN |
| Immunogen Region: |
1300-1600 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1300-1600 of human KIF13A (NP_001099036.1). |
| Immunogen Sequence: |
SCGVTYEIVSNIPKATEEIE DRETLALLAARSENEGTSDG ETYIEKYTRGVLQVENILSL ERLRQAVTVKEALSTKARHI RRSLSTPNVHNVSSSRPDLS GFDEDDKGWPENQLDMSDYS SSYQDVACYGTLPRDSPRRN KEGCTSETPHALTVSPFKAF SPQPPKFFKPLMPVKEEHKK RIALEARPLLSQEDSEEEEN ELEAINRKLISSQPYVPVEF ADFSVYNASLENREWFSSK |
| Tissue Specificity | Widely expressed, with highest levels in heart, brain and skeletal muscle. |
| Function | Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis. |
| Protein Name | Kinesin-Like Protein Kif13aKinesin-Like Protein Rbkin |
| Database Links | Reactome: R-HSA-390471 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeMidbodyEndosome MembraneGolgi Apparatus MembraneRecruited To The Midbody During Cytokinesis |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif13a antibodyAnti-Kinesin-Like Protein Rbkin antibodyAnti-KIF13A antibodyAnti-RBKIN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
