| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-KCNQ4 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-1-3µg/mlELISA-antibody detection limit dilution 1:4000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
KCNQ4 |
| Gene ID: |
9132 |
| Uniprot ID: |
KCNQ4_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_004691.2; NP_751895.1 |
| Specificity: |
This antibody is expected to recognise both reported isoforms (NP_004691.2; NP_751895.1) ; may cross-react in Mouse; |
| Immunogen Sequence: |
DKGPSDAEVVDE |
| Function | Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors. |
| Protein Name | Potassium Voltage-Gated Channel Subfamily Kqt Member 4Kqt-Like 4Potassium Channel Subunit Alpha Kvlqt4Voltage-Gated Potassium Channel Subunit Kv7.4 |
| Database Links | Reactome: R-HSA-1296072Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
| Cellular Localisation | Basal Cell MembraneMulti-Pass Membrane ProteinSituated At The Basal Membrane Of Cochlear Outer Hair Cells |
| Alternative Antibody Names | Anti-Potassium Voltage-Gated Channel Subfamily Kqt Member 4 antibodyAnti-Kqt-Like 4 antibodyAnti-Potassium Channel Subunit Alpha Kvlqt4 antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv7.4 antibodyAnti-KCNQ4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
