Anti-KCNMB2 antibody (STJ13100160)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from human KCNMB2 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat and mouse.
General Information
| Short Description | Rabbit polyclonal anti-KCNMB2 for use in IHC and WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:5000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | KCNMB2 |
| Gene ID | 10242 |
| Uniprot ID | KCMB2_HUMAN |
| Immunogen | A synthetic peptide from human KCNMB2 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat and mouse. |
| Specificity | Specific for KCNMB2. |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons. |
| Protein Name | Calcium-Activated Potassium Channel Subunit Beta-2Bk Channel Subunit Beta-2Bkbeta2Hbeta2Calcium-Activated Potassium Channel - Subfamily M Subunit Beta-2Charybdotoxin Receptor Subunit Beta-2Hbeta3K(Vcabeta-2Maxi K Channel Subunit Beta-2Slo-Beta-2 |
| Database Links | Reactome: R-HSA-1296052Reactome: R-HSA-418457 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Calcium-Activated Potassium Channel Subunit Beta-2 antibodyAnti-Bk Channel Subunit Beta-2 antibodyAnti-Bkbeta2 antibodyAnti-Hbeta2 antibodyAnti-Calcium-Activated Potassium Channel - Subfamily M Subunit Beta-2 antibodyAnti-Charybdotoxin Receptor Subunit Beta-2 antibodyAnti-Hbeta3 antibodyAnti-K(Vcabeta-2 antibodyAnti-Maxi K Channel Subunit Beta-2 antibodyAnti-Slo-Beta-2 antibodyAnti-KCNMB2 antibody |
Information sourced from Uniprot.org