Anti-KCNMB2 antibody (STJ13100160)

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STJ13100160-100
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Host: Rabbit
Applications: IHC/WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-KCNMB2 is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Lyophilised
Purification: IgG purified
Dilution Range: IHC, WB. A dilution of 1:5000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage Instruction: Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol: KCNMB2
Gene ID: 10242
Uniprot ID: KCMB2_HUMAN
Specificity: Specific for KCNMB2.
Immunogen: A synthetic peptide from human KCNMB2 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat and mouse.
Post Translational Modifications N-glycosylated.
Function Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
Protein Name Calcium-Activated Potassium Channel Subunit Beta-2
Bk Channel Subunit Beta-2
Bkbeta2
Hbeta2
Calcium-Activated Potassium Channel - Subfamily M Subunit Beta-2
Charybdotoxin Receptor Subunit Beta-2
Hbeta3
K(Vcabeta-2
Maxi K Channel Subunit Beta-2
Slo-Beta-2
Database Links Reactome: R-HSA-1296052
Reactome: R-HSA-418457
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Calcium-Activated Potassium Channel Subunit Beta-2 antibody
Anti-Bk Channel Subunit Beta-2 antibody
Anti-Bkbeta2 antibody
Anti-Hbeta2 antibody
Anti-Calcium-Activated Potassium Channel - Subfamily M Subunit Beta-2 antibody
Anti-Charybdotoxin Receptor Subunit Beta-2 antibody
Anti-Hbeta3 antibody
Anti-K(Vcabeta-2 antibody
Anti-Maxi K Channel Subunit Beta-2 antibody
Anti-Slo-Beta-2 antibody
Anti-KCNMB2 antibody

Information sourced from Uniprot.org

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