| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KAT6B (400-500) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KAT6B |
| Gene ID: |
23522 |
| Uniprot ID: |
KAT6B_HUMAN |
| Immunogen Region: |
400-500 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human KAT6B (NP_001243398.1). |
| Immunogen Sequence: |
DLDVFKQAQELSWEKIECES GVEDCGRYPSVIEFGKYEIQ TWYSSPYPQEYARLPKLYLC EFCLKYMKSKNILLRHSKKC GWFHPPANEIYRRKDLSVFE V |
| Tissue Specificity | Ubiquitously expressed, with high levels in heart, pancreas, testis and ovary. |
| Post Translational Modifications | Autoacetylated. Autoacetylation at Lys-815 is required for proper function. |
| Function | Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. |
| Protein Name | Histone Acetyltransferase Kat6bHistone Acetyltransferase Moz2Moz - Ybf2/Sas3 - Sas2 And Tip60 Protein 4Myst-4Monocytic Leukemia Zinc Finger Protein-Related Factor |
| Database Links | Reactome: R-HSA-3214847 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone Acetyltransferase Kat6b antibodyAnti-Histone Acetyltransferase Moz2 antibodyAnti-Moz - Ybf2/Sas3 - Sas2 And Tip60 Protein 4 antibodyAnti-Myst-4 antibodyAnti-Monocytic Leukemia Zinc Finger Protein-Related Factor antibodyAnti-KAT6B antibodyAnti-KIAA0383 antibodyAnti-MORF antibodyAnti-MOZ2 antibodyAnti-MYST4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
