Anti-KAT6B antibody (400-500) (STJ119314)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal KAT6B (400-500) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KAT6B |
| Gene ID | 23522 |
| Uniprot ID | KAT6B_HUMAN |
| Immunogen Region | 400-500 |
| Immunogen Sequence | DLDVFKQAQELSWEKIECES GVEDCGRYPSVIEFGKYEIQ TWYSSPYPQEYARLPKLYLC EFCLKYMKSKNILLRHSKKC GWFHPPANEIYRRKDLSVFE V |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human KAT6B (NP_001243398.1). |
Additional Info
| Tissue Specificity | Ubiquitously expressed, with high levels in heart, pancreas, testis and ovary. |
| Post Translational Modifications | Autoacetylated. Autoacetylation at Lys-815 is required for proper function. |
| Function | Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. |
| Protein Name | Histone Acetyltransferase Kat6bHistone Acetyltransferase Moz2Moz - Ybf2/Sas3 - Sas2 And Tip60 Protein 4Myst-4Monocytic Leukemia Zinc Finger Protein-Related Factor |
| Database Links | Reactome: R-HSA-3214847 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone Acetyltransferase Kat6b antibodyAnti-Histone Acetyltransferase Moz2 antibodyAnti-Moz - Ybf2/Sas3 - Sas2 And Tip60 Protein 4 antibodyAnti-Myst-4 antibodyAnti-Monocytic Leukemia Zinc Finger Protein-Related Factor antibodyAnti-KAT6B antibodyAnti-KIAA0383 antibodyAnti-MORF antibodyAnti-MOZ2 antibodyAnti-MYST4 antibody |
Information sourced from Uniprot.org