| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITPKB |
| Gene ID: | 3707 |
| Uniprot ID: | IP3KB_HUMAN |
| Immunogen Region: | 1-260 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ITPKB (NP_002212.3). |
| Immunogen Sequence: | MAVYCYALNSLVIMNSANEM KSGGGPGPSGSETPPPPRRA VLSPGSVFSPGRGASFLFPP AESLSPEEPRSPGGWRSGRR RLNSSSGSGSGSSGSSVSSP SWAGRLRGDRQQVVAAGTLS PPGPEEAKRKLRILQRELQN VQVNQKVGMFEAHIQAQSSA IQAPRSPRLGRARSPSPCPF RSSSQPPGRVLVQGARSEER RTKSWGEQCPETSGTDSGRK GGPSLCSSQVKKGMPPLPG |
| Function | Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis. |
| Protein Name | Inositol-Trisphosphate 3-Kinase BInositol 1 -4 -5-Trisphosphate 3-Kinase BIp3 3-Kinase BIp3k BInsp 3-Kinase B |
| Database Links | Reactome: R-HSA-1855204 |
| Cellular Localisation | CytoplasmCytoskeletonEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Inositol-Trisphosphate 3-Kinase B antibodyAnti-Inositol 1 -4 -5-Trisphosphate 3-Kinase B antibodyAnti-Ip3 3-Kinase B antibodyAnti-Ip3k B antibodyAnti-Insp 3-Kinase B antibodyAnti-ITPKB antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and APEH knockout (KO) 293T cells, using [KO Validated] APEH Rabbit polyclonal antibody (STJ11100788) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89724/358205/STJ11100788_1__51624.1713122526.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and APEH knockout (KO) 293T cells, using [KO Validated] APEH Rabbit polyclonal antibody (STJ11100788) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
