• Western blot analysis of extracts of various cell lines, using ITPKB antibody (STJ24265) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-ITPKB antibody (1-260) (STJ24265)

SKU:
STJ24265

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ITPKB (1-260) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ITPKB
Gene ID: 3707
Uniprot ID: IP3KB_HUMAN
Immunogen Region: 1-260
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ITPKB (NP_002212.3).
Immunogen Sequence: MAVYCYALNSLVIMNSANEM KSGGGPGPSGSETPPPPRRA VLSPGSVFSPGRGASFLFPP AESLSPEEPRSPGGWRSGRR RLNSSSGSGSGSSGSSVSSP SWAGRLRGDRQQVVAAGTLS PPGPEEAKRKLRILQRELQN VQVNQKVGMFEAHIQAQSSA IQAPRSPRLGRARSPSPCPF RSSSQPPGRVLVQGARSEER RTKSWGEQCPETSGTDSGRK GGPSLCSSQVKKGMPPLPG
Function Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis.
Protein Name Inositol-Trisphosphate 3-Kinase B
Inositol 1 -4 -5-Trisphosphate 3-Kinase B
Ip3 3-Kinase B
Ip3k B
Insp 3-Kinase B
Database Links Reactome: R-HSA-1855204
Cellular Localisation Cytoplasm
Cytoskeleton
Endoplasmic Reticulum
Alternative Antibody Names Anti-Inositol-Trisphosphate 3-Kinase B antibody
Anti-Inositol 1 -4 -5-Trisphosphate 3-Kinase B antibody
Anti-Ip3 3-Kinase B antibody
Anti-Ip3k B antibody
Anti-Insp 3-Kinase B antibody
Anti-ITPKB antibody

Information sourced from Uniprot.org

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