| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ITGAX (146-342) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ITGAX |
| Gene ID: |
3687 |
| Uniprot ID: |
ITAX_HUMAN |
| Immunogen Region: |
146-342 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 146-342 of ITGAX (NP_000878.2). |
| Immunogen Sequence: |
PRQEQDIVFLIDGSGSISSR NFATMMNFVRAVISQFQRPS TQFSLMQFSNKFQTHFTFEE FRRSSNPLSLLASVHQLQGF TYTATAIQNVVHRLFHASYG ARRDAAKILIVITDGKKEGD SLDYKDVIPMADAAGIIRYA IGVGLAFQNRNSWKELNDIA SKPSQEHIFKVEDFDALKDI QNQLKEKIFAIEGTETT |
| Tissue Specificity | Predominantly expressed in monocytes and granulocytes. |
| Function | Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. |
| Protein Name | Integrin Alpha-XCd11 Antigen-Like Family Member CLeu M5Leukocyte Adhesion Glycoprotein P150 -95 Alpha ChainLeukocyte Adhesion Receptor P150 -95Cd Antigen Cd11c |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-216083Reactome: R-HSA-3000178Reactome: R-HSA-6785807Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-X antibodyAnti-Cd11 Antigen-Like Family Member C antibodyAnti-Leu M5 antibodyAnti-Leukocyte Adhesion Glycoprotein P150 -95 Alpha Chain antibodyAnti-Leukocyte Adhesion Receptor P150 -95 antibodyAnti-Cd Antigen Cd11c antibodyAnti-ITGAX antibodyAnti-CD11C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![C57BL/6 murine splenocytes were stained with Anti-CD11c antibody (STJA0000071) [Used at 0.2 µg/10<sup>6</sup> cells dilution] and Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC Conjugated). Splenocytes stained with Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC Conjugated) (Right) were used as control](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/144924/291593/STJA0000071_1__59322.1631205374.jpg?c=1 "C57BL/6 murine splenocytes were stained with Anti-CD11c antibody (STJA0000071) [Used at 0.2 µg/10<sup>6</sup> cells dilution] and Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC Conjugated). Splenocytes stained with Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC Conjugated) (Right) were used as control")