Anti-Isocitrate Dehydrogenenase 1 IDH1-R132H antibody [HMab-1] (STJ16101369)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenKLH-conjugated peptide human IDH1
General Information
| Short Description | Mouse monoclonal anti-Isocitrate Dehydrogenenase 1 IDH1-R132H for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | HMab-1 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Dilution Range | IHC-P 1:25-1:50 |
| Formulation | Tissue culture supernatant with sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | KLH-conjugated peptide human IDH1 |
Additional Info
| Background | Monoclonal Anti-IDH1 (R132H) recognizes only the R132H mutation of human IDH1 (R132H) and does not cross react with other mutations. The most frequent known mutation (>90%) is the alteration of arginine to histidine (R132H).6. Hence, antibodies that recognize the IDH1R132H mutation can be useful for the diagnosis of mutation-bearing tumors like gliomas. Positive control Human Glioma tissue |
Information sourced from Uniprot.org