| Host: |
Mouse |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Isocitrate Dehydrogenenase 1 IDH1-R132H is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
HMab-1 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1k |
| Formulation: |
Tissue culture supernatant with sodium azide |
| Concentration: |
Lot specific |
| Dilution Range: |
IHC-P 1:25-1:50 |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Immunogen: |
KLH-conjugated peptide human IDH1 |
| Background | Monoclonal Anti-IDH1 (R132H) recognizes only the R132H mutation of human IDH1 (R132H) and does not cross react with other mutations. The most frequent known mutation (>90%) is the alteration of arginine to histidine (R132H).6. Hence, antibodies that recognize the IDH1R132H mutation can be useful for the diagnosis of mutation-bearing tumors like gliomas. Positive control Human Glioma tissue |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Anti-Isocitrate Dehydrogenenase 1 IDH1-R132S antibody [SMab-1] (STJ16101370)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/151879/346964/STJ16101370_1__82391.1681999195.jpg?c=1 "Anti-Isocitrate Dehydrogenenase 1 IDH1-R132S antibody [SMab-1] (STJ16101370)")
![Western blot analysis of lysates from wild type (WT) and IDH1 knockout (KO) HeLa cells, using [KO Validated] IDH1 Rabbit polyclonal antibody (STJ119996) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98781/382830/STJ119996_1__99034.1713151333.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and IDH1 knockout (KO) HeLa cells, using [KO Validated] IDH1 Rabbit polyclonal antibody (STJ119996) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.")
