| Short Description : | Goat polyclonal antibody anti-IRF2BP2 (Internal) is suitable for use in ELISA research applications. |
| Applications: | Pep-ELISA |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments gave an approx 80kDa band in Mouse fetal Lung lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | IRF2BP2 |
| Gene ID: | 359948 |
| Uniprot ID: | I2BP2_HUMAN |
| Accession Number: | NP_892017.2; NP_001070865.1 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | QHGHSGPFESKFK |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_892017.2; NP_001070865.1). |
| Function | Acts as a transcriptional corepressor in a IRF2-dependent manner.this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles. Plays a role in immature B-cell differentiation. |
| Protein Name | Interferon Regulatory Factor 2-Binding Protein 2Irf-2-Binding Protein 2Irf-2bp2 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Interferon Regulatory Factor 2-Binding Protein 2 antibodyAnti-Irf-2-Binding Protein 2 antibodyAnti-Irf-2bp2 antibodyAnti-IRF2BP2 antibody |
Information sourced from Uniprot.org
